Fulminant Cushing's syndrome due to an ACTH-producing thymic carcinoid.
نویسندگان
چکیده
Case Description A 32-year-old man was hospitalized because of severe fatigue and blurred vision. Evaluation revealed glaucoma, hypertension, new-onset diabetes mellitus and severe hypokalemia with metabolic alkalosis. A month later he was admitted to the urology department because of a perianal and scrotal abscess, which was surgically drained. Following surgery, he developed shortness of breath and hypoxia. Chest X-ray and a spiral computed tomography scan showed massive atelectasis of the left lower lobe with consolidation of the left upper lobe and multiple thrombi in the right and left pulmonary tree. An anterior mediastinal mass was also seen. Three days later he was admitted to our medical intensive care unit with respiratory insufficiency. On admission the patient was in respiratory distress (40 breaths/min), with
منابع مشابه
Cyclical Cushing's syndrome due to an atypical thymic carcinoid.
A 43-year-old man presented with fluctuating symptoms of weight gain, shortness of breath, pretibial oedema, associated with anxiety and memory disturbances. Laboratory investigation revealed an adrenocorticotropin (ACTH)-dependent cyclical Cushing's syndrome characterised by remarkable variations in urinary cortisol excretions ranging from 27 to 28,050 nmol/ 24 h. Magnetic resonance imaging (M...
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To differentiate between ectopic ACTH syndrome and Cushing's disease, gene expression of corticotropin-releasing hormone (CRH), proopiomelanocortin (POMC), and glucocorticoid receptor was examined in 10 pituitary adenomas (Cushing's disease) and in 10 ectopic ACTH-producing tumors. CRH increased plasma ACTH levels in all patients with Cushing's disease and in five patients with ectopic ACTH syn...
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ورودعنوان ژورنال:
- The Israel Medical Association journal : IMAJ
دوره 2 8 شماره
صفحات -
تاریخ انتشار 2000